Good night. I’m Karen Kaplan, and it’s Friday, Oct. 22. Right here’s the newest on what’s occurring with the coronavirus in California and past.
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Chances are you’ll often obtain promotional content material from the Los Angeles Occasions.
In-N-Out has been serving hamburgers since 1948. That’s the enterprise it is aware of. However now San Francisco needs it so as to add some gentle regulation enforcement to the menu — and the restaurant chain isn’t blissful about it.
How sad? In-N-Out would slightly let well being inspectors shut its Fisherman’s Wharf location than make prospects present image ID and proof of COVID-19 vaccination.
“As an organization, In-N-Out Burger strongly believes within the highest type of customer support and to us which means serving all prospects who go to us and making all prospects really feel welcome,” mentioned Arnie Wensinger, the chain’s chief authorized and enterprise officer. “We refuse to grow to be the vaccination police for any authorities.”
In-N-Out was prepared to place up indicators informing patrons that, in San Francisco, diners have been required to point out proof of vaccination in the event that they needed to eat indoors. These indicators have been “correctly and clearly” posted, Wensinger mentioned.
However truly asking for that documentation — not to mention turning away prospects who lacked it — could be going too far.
“We fiercely disagree with any authorities dictate that forces a non-public firm to discriminate in opposition to prospects who select to patronize their enterprise,” the lawyer mentioned in a press release.

The In-N-Out Burger at San Francisco’s Fisherman’s Wharf.
(Alex Tai / Getty Pictures)
That’s a method to have a look at it. Right here’s one other: COVID-19 is a contagious respiratory illness that has killed greater than 70,000 Californians and greater than 733,000 People.
COVID-19 vaccines are the best way to show that round — and the extra, the higher.
“Vaccines stay our greatest instrument to struggle this illness and are available out of the pandemic,” mentioned the San Francisco Division of Public Well being, which shut down the In-N-Out. “Vaccination is notably essential in a public indoor setting the place teams of individuals are gathering and eradicating their masks, elements that make it simpler for the virus to unfold. That’s the reason San Francisco requires proof of vaccination for indoor eating.”
Many restaurant operators within the metropolis appear to agree. Almost 4 out of 5 food-service companies polled by the Golden Gate Restaurant Assn. mentioned asking prospects to point out proof of vaccination earlier than serving them indoors was truly fairly straightforward.
“Does it put a burden on you? Do you must add just a little extra staffing? Does it put individuals probably in battle? Sadly, it does,” Laurie Thomas, the group’s govt director, told my colleagues. “However, actually, it has been a lot much less of an issue than anyone anticipated.”
In Los Angeles County, eating places are inspired to ask prospects eating indoors for proof of vaccination, but it surely’s not strictly required. On Nov. 8, eating places in L.A. metropolis limits will be subject to a rule like the one in San Francisco. (Town ordinance will even apply to gyms, shops, film theaters and different indoor venues.)
The San Francisco well being division says In-N-Out has “taken steps to conform” with its guidelines and is as soon as once more serving prospects at Fisherman’s Wharf — for out of doors seating or takeout solely.
By the numbers
California circumstances and deaths as of three:30 p.m. Friday:

Observe California’s coronavirus spread and vaccination efforts — together with the newest numbers and the way they break down — with our graphics.
A coronavirus conundrum
Think about it have been as much as you to determine whether or not to present somebody a COVID-19 booster shot. You’d in all probability need to know how a lot immunity that particular person already had so that you just didn’t topic them to an pointless needle stick (and the small danger of adversarial results that include it). That info would additionally be certain that you didn’t withhold a shot from somebody who wanted it.
That is hardly a radical idea. Docs solely prescribe statin medication to individuals after a blood take a look at reveals they’ve excessive ldl cholesterol. Likewise, nobody will ask you to inject your self with insulin until you could have a bona fide case of diabetes.
The issue with COVID-19 boosters is that scientists haven’t provide you with a approach to check whether or not an individual’s vaccine safety has worn off. It would take years for them to search out one — assuming they ever do.
There’s no query that some individuals want booster pictures. Loads of information from the actual world present that vaccine safety is waning, particularly on the subject of their capacity to stop gentle and average sickness.
However seeing a necessity for boosters typically isn’t the identical as determining when a specific particular person ought to get an additional shot within the arm. To do this, scientists want “a typical forex by which individuals’s ranges of safety will be reliably measured, valued and in contrast,” my colleague Melissa Healy explains. “If it rises, which means an individual’s defenses are stronger; if it falls, they’ve grow to be extra weak.”
The perfect candidate could be straightforward to measure (no biopsies, please) with a take a look at that produces correct outcomes and doesn’t break the financial institution. If the take a look at outcomes fall under a sure threshold, you’d know a booster shot was so as.
Proper now, coronavirus antibodies are the closest factor we now have. Their ranges rise proper after a dose of vaccine (or a real an infection) after which decay over time. However we all know that’s not the entire story.

A nurse masses a syringe with the Pfizer COVID-19 vaccine.
(Rogelio V. Solis / Related Press)
Even after antibody ranges wane, the immune system nonetheless protects with so-called reminiscence cells like B cells and T cells. Sadly, it’s unclear how reminiscence cells are correlated with the general power of the immune system’s capacity to fend off the coronavirus.
After which there are lymph nodes, white blood cells and different issues within the combine. Their relative significance can shift over time, so your take a look at outcomes may change though your immune safety doesn’t.
Within the midst of all this complexity, discovering one single factor to measure is like taking part in “three-dimensional chess,” mentioned Dr. Archana Chatterjee, a pediatric infectious illness skilled on the College of Chicago who serves on a panel that advises the Meals and Drug Administration about vaccines.
Certainly, a number of members of that advisory panel lamented the shortage of a coronavirus immunity metric as they debated whether or not to suggest COVID-19 booster pictures.
It’s “one of many struggles we’re all having,” mentioned Dr. Hayley Gans, a pediatric infectious illness specialist at Stanford College.
California’s vaccination progress


See the newest on California’s vaccination progress with our tracker.
In different information …
Are you uninterested in COVID-19 vaccines but? No? Good, as a result of extra of them are on the best way.
The variety of People eligible for booster pictures has elevated by hundreds of thousands now that the FDA and Facilities for Illness Management and Prevention have signed off on extra doses for individuals who acquired the Moderna or Johnson & Johnson vaccines the primary time round.
The rules for Moderna people are the identical as for individuals who acquired the Pfizer-BioNTech vaccine: They’re suggested to get it if they’re at the least 65 years outdated, in the event that they dwell in a nursing dwelling or comparable group setting, or in the event that they’re at elevated danger of turning into severely in poor health with COVID-19 due to a preexisting well being drawback.
As well as, booster pictures can be found to adults of any age in the event that they’re at elevated danger of COVID-19 due to their well being, their dwelling scenario or their jobs. That final class covers individuals like healthcare staff and lecturers.
The Moderna booster pictures comprise half the dose used within the main sequence. To be eligible, the second dose will need to have been given at the least six months earlier.
The recommendation is totally different for individuals who acquired the J&J vaccine: Everybody in that group is suggested to get a booster in the event that they acquired their preliminary jab at the least two months in the past. The one-dose vaccine has not supplied as a lot safety because the two-dose choices, however including a booster after a shorter delay will help make up the gap, advisors mentioned.
And so as to add just a little pleasure for everybody, regulators will now enable individuals to “combine and match” their booster pictures, so they can switch to another brand in the event that they’d like. Not having to trace down a particular sort of shot ought to make the method extra handy, officers mentioned.
There are different causes to think about a mix-and-match booster too. As an illustration, youthful girls who acquired the J&J vaccine the primary time round may go for one of many mRNA vaccines as a booster to keep away from the small risk of a rare blood-clotting disorder, an issue that prompted regulators to “pause” the usage of that vaccine for 10 days this spring. Equally, youthful males who began out with an mRNA vaccine may need to swap to the J&J shot to keep away from a small risk of myocarditis, an irritation of the center muscle.
A government-sponsored examine on the potential advantages of various combos is ongoing, and preliminary information counsel individuals vaccinated with the Johnson & Johnson shot produced extra coronavirus-fighting antibodies after they have been boosted with the Pfizer or Moderna vaccines. That prompted some members of the CDC’s vaccine advisory panel to counsel that J&J recipients swap manufacturers for his or her booster.
Subsequent week, an FDA advisory panel will look at information on Pfizer’s vaccine for children ages 5 to 11. On Friday, the corporate mentioned its medical trial confirmed the vaccine was protected and that it diminished the danger of growing COVID-19 by 91%.
Pfizer examined kid-sized doses that have been one-third the dimensions of doses given to teenagers and adults. The trial concerned practically 2,300 kids and was carried out throughout August and September, when the Delta variant was the dominant coronavirus pressure.
The corporate mentioned there have been three circumstances of COVID-19 among the many kids who have been randomly chosen to get the vaccine and 16 circumstances amongst those that acquired a placebo.
As well as, Pfizer mentioned the smaller dose prompted an antibody response in younger kids that was equal to the response seen in teenagers and adults who obtained the full-strength pictures.
If the vaccine is permitted for this age group — one thing specialists think about doubtless — roughly 28 million further kids could be eligible for immunization sometime in November. The pictures are packaged in vials with orange caps in order that they gained’t be mistaken for the grownup model.
The Biden administration is already planning for the rollout. As soon as an emergency use authorization comes by means of, the shots will be available in additional than 25,000 pediatricians’ places of work, tens of 1000’s of pharmacies and presumably even at faculties, in keeping with the White Home.
The particular vials can be able to ship inside hours of authorization, together with smaller needles to manage the vaccine. About 15 million doses are anticipated to be distributed through the first week.
“We’re going to be prepared, pending the FDA and CDC determination,” White Home COVID-19 coordinator Jeff Zients mentioned Wednesday.
Docs are already bracing for a tsunami of sufferers.
“Judging by the variety of calls, I believe we’re going to be slammed for the primary a number of weeks,” mentioned Dr. Sterling Ransone, who has a apply in Deltaville, Va., and serves as president of the American Academy of Household Physicians.
And eventually, right here’s some recent proof that each one the fuss is price it: Two new studies present that the Pfizer-BioNTech vaccine works properly in teenagers in real-world circumstances.
The medical trials that examined the vaccine in teenagers have been carried out earlier than the Delta variant turned the dominant pressure. Since Delta spreads extra readily than its predecessors, there have been questions on its effectiveness.
One report, revealed within the New England Journal of Drugs, discovered that the vaccine was 90% efficient at decreasing the danger of coronavirus infections one to 3 weeks after the second dose. It was additionally 93% efficient at decreasing the danger of growing COVID-19 signs.
The second report, revealed by the CDC, concluded that the vaccine diminished teenagers’ danger of being hospitalized for COVID-19 by 93%. The examine recognized 77 sufferers who have been handled within the intensive care unit, together with two who died. Not one of the ICU sufferers had been vaccinated.
The examine “reinforces the significance of vaccination to guard U.S. youths in opposition to extreme COVID-19,” the authors wrote.
Your questions answered
In the present day’s query comes from readers who need to know: Will we now have to fret about coronavirus variants perpetually?
If not perpetually, then for a long, long time.
It’s the nature of viruses to mutate — each time they copy themselves inside an contaminated particular person, there’s an opportunity to make a mistake with the genetic code. A mistake that helps a virus survive is sure to unfold.
Greater than half the world stays unvaccinated, so the coronavirus has loads of alternative forward of it. However the extra time that passes, the extra a virus adapts to its host. That leaves fewer alternatives for large modifications to happen.
“We’ve seen a stage of speedy evolution for the virus,” mentioned Dr. Adam Lauring, a virus and infectious illness skilled on the College of Michigan. “It’s been harvesting the low-hanging fruit, however there’s not an infinite variety of issues it will possibly do.”
Nevertheless it might nonetheless change sufficient to sneak previous the antibodies produced by COVID-19 vaccines or left behind from a earlier an infection. If that’s the case, it will make sense to tweak the vaccine periodically, the best way we do with flu pictures.
We need to hear from you. Email us your coronavirus questions, and we’ll do our greatest to reply them. Questioning in case your query’s already been answered? Take a look at our archive here.
The pandemic in footage

“This motel is the final cease for a lot of,” says Jake Crandall, who manages the Desert Moon in Las Vegas. “It’s both right here or the streets.”
(Francine Orr / Los Angeles Occasions)
Hundreds of thousands of People are nonetheless struggling the financial fallout from the pandemic, together with roughly 10 million people who find themselves behind on their lease. And with the expiration of eviction moratoriums, 1000’s of them are calling locations just like the Desert Moon Motel dwelling.
The Desert Moon was constructed within the Nineteen Thirties and sits a few dozen blocks from the glitz of downtown Las Vegas. My colleagues Kurtis Lee and Francine Orr got to know some of the folks who scrape collectively $57 an evening to safe their spot there.
There are younger adults struggling to determine themselves. There are households who have been priced out of California. There are individuals who ought to be considering retirement however discover themselves again at sq. one. They’re grateful to be sleeping in beds as an alternative of their vehicles.
“Everybody deserves a roof over their head,” mentioned Kelly Robson, the chief social companies officer for a neighborhood nonprofit that works to get individuals off the streets. “Folks deserve dignity and respect.”
Sources
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